Back to results
US 2004/0171085 A1Published application
Methods and compositions for treating neurodegenerative diseases
AssigneeIrm LLC
InventorClaudio A.P. Joazeiro
Life of this patent
Estimating the term…
Abstract
Methods and compositions for treating neurodegenerative diseases by modulating the interaction of ubiquitin to ubiquitin binding motifs are provided.
Claims23
A method of identifying an agent for treating a neurodegenerative disease, the method comprising,
- identifying an agent that inhibits binding of ubiquitin to a ubiquitin binding motif of a polypeptide.
A method of identifying a gene product that modulates polyglutamine aggregate (polyQ) formation, the method comprising,
- expressing a plurality of polynucleotides in a plurality of cells;
- and
- detecting the effect of the expression on polyQ aggregate formation in the cells.
Dependencies are inferred from the claim text.