Probe carrier, method of producing the probe carrier, method of evaluating the probe carrier and method of detecting a target nucleic acid using the same
AssigneeCanon Kabushiki Kaisha
InventorKazuhiro Takada
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Abstract
To provide probe carrier having a structure that a single-stranded DNA probe can be immobilized to a carrier effectively and forms of probe dots or spots immobilized to the carrier can be observed accurately by a scanning probe microscope or its derivative technology. A gold-containing film is formed in an area of the carrier where the single-stranded DNA probe is immobilized and the single-stranded DNA probe is immobilized to this film through a sulfur atom.
Claims19
A probe carrier, characterized by comprising a single-stranded DNA probe immobilized to a carrier having a thin film containing (111)-oriented single crystal gold formed thereon through a sulfur atom.
A method of producing a probe carrier having a single-stranded DNA probe immobilized to a carrier having a thin film containing (111)-oriented single crystal gold formed thereon through a sulfur atom, the method comprising the steps of:
- forming the thin film containing (111)-oriented single crystal gold on the carrier;
- and
- immobilizing the single-stranded DNA probe to the thin film through the sulfur atom.
A molecular device manufactured by using a thin film containing (111)-oriented single crystal gold as electrodes and interconnecting the electrodes by using a molecular chain typified by DNA.
Dependencies are inferred from the claim text.