US 2004/0171012 A1Published application

Nucleic acid-associated proteins

OwnerHenry Yue, Y Tom Tang +31inventors

InventorsHenry Yue, Y Tom Tang, Mariah R Baughn, Shanya D Becha, Bridget A Warren, Narinder K Chawla, Preeti G Lal, Ernestine A Lee, April J A Hafalia, Thomas W Richardson, Jennifer A Griffin, Brooke M Emerling, Jayalaxmi Ramkumar, Huibin Yue, Anita Swarnakar, Bao Tran, Joana X Li, Monique G Yao, Junming Yang, Craig H Ison, Ian J Forsythe, Cynthia D Honchell, Vicki S Elliott, Yan Lu, Li Ding, Wen Luo, Yu-Mei E Wang, Neil Burford, Mark L Borowsky, Danniel B Nguyen, Anna M Chinn, Amy E Kable, Chandra S Arvizu

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Abstract

Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

Claims115

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-30,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-2, SEQ ID NO:5-7, SEQ ID NO:9-19, and SEQ ID NO:21-28,
c) a polypeptide comprising a naturally occurring amino acid sequence at least 97% identical to the amino acid sequence of SEQ ID NO:4,
d) a polypeptide comprising a naturally occurring amino acid sequence at least 98% identical to the amino acid sequence of SEQ ID NO:29,
e) a polypeptide comprising a naturally occurring amino acid sequence at least 99% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:3 and SEQ ID NO:30,
f) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-30, and
g) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-30.

4 more elements

Dependencies are inferred from the claim text.

Facts

Application: 10/479,435Filed 1 Dec 2003
Priority: 1 Jun 2001
Published: 2 Sep 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification44 codes

C07K 14/47
From vertebrates: from mammals
A61P 1/16
Drugs for disorders of the alimentary tract or the digestive system: for liver or gallbladder disorders, e.g. hepatoprotective agents,…
A61P 3/00
Drugs for disorders of the metabolism
A61P 5/00
Drugs for disorders of the endocrine system

Family

Application60/295,359Us provisional application · filed 1 Jun 2001
Application60/297,222Us provisional application · filed 8 Jun 2001
Application60/296,878Us provisional application · filed 8 Jun 2001
Application60/298,665Us provisional application · filed 15 Jun 2001
Application60/298,693Us provisional application · filed 15 Jun 2001
Application60/298,615Us provisional application · filed 15 Jun 2001
Application60/300,176Us provisional application · filed 21 Jun 2001
Application60/373,891Us provisional application · filed 19 Apr 2002
US 2004/0171012 A1This patent

From the US filing history. Foreign family members aren’t listed.