US 2004/0171009 A1Published application

Lipid-associated molecules

OwnerY. Tom Tang, Henry Yue +23inventors

InventorsY. Tom Tang, Henry Yue, Yalda Azimzai, Mariah R. Baughn, Neil Burford, Roopa M. Reddy, Narinder K. Chawla, Debopriya Das, Danniel B. Nguyen, Monique G. Yao, Chandra S. Arvizu, Yan Lu, Ameena R. Gandhi, Jennifer A. Griffin, Vicki S. Elliott, Jayalaxmi Ramkumar, Preeti G. Lal, Dyung Aina M. Lu, Ernestine A. Lee, Soo Yeun Lee, Huibin Yue, Junming Yang, Catherine M. Tribouley, Amy E. Kable, Anita Swarnakar

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Abstract

The invention provides human lipid-associated molecules (LIPAM) and polynucleotides which identify and encode LIPAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPAM.

Claims75

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-10,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1, SEQ ID NO:3, and SEQ ID NO:5-10,
c) a polypeptide comprising a naturally occurring amino acid sequence at least 99% identical to the amino acid sequence of SEQ ID NO:2,
d) a polypeptide comprising a naturally occurring amino acid sequence at least 97% identical to the amino acid sequence of SEQ ID NO:4,
e) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-10, and
f) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-10.

3 more elements

Dependencies are inferred from the claim text.