Poly(vinyl alcohol) coated capillaries
OwnerTohei Moritani, Benjamin Chuinventors
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Abstract
Coated fused silica capillaries useful for capillary electrophoresis are disclosed. The coating materials used are the copolymer comprising comonomer units represented by the formulae: 1 whrein a, b and c are molar fractions having the values from 0 to 100 mol %. This coating improves stability and resolution dramatically in the analytical separation of capillary electrophoresis for ionic molecules such as DNA, proteins or small molecules. The new coating capillaries are much more advantageous in reliability and facility than the similar prior arts of coated capillaries where the three sensitive reaction steps, covalently bonding monomer group, polymerization and hydrolysis, are carried out inside capillaries.
Claims8
A capillary, the inner surface of which is coated by the treatment of the copolymer comprising comonomer units represented by the formulae:
- 5
- whrein R is a lower alkyl group, B is an alkali metal, and a, b and c are molar fractions having the values from 0 to 100 mol %.
Dependencies are inferred from the claim text.