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US 2004/0170689 A1Published application
Stabilized formulations comprising hydrolytically unstable compositions
OwnerDebra Alida Odink, I-Lan Sue +1inventors
InventorsDebra Alida Odink, I-Lan Sue, Gary Conard Visor
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Abstract
This invention relates to new stable oral pharmaceutical formulations prepared by covering an nucleus formed by a core with a first hydrophobic polymer layer, a second layer coating the first layer, wherein said second layer comprises one or more labile pharmaceutical compounds in one or more acceptable hydrophobic excipients, and an optional third enteric polymer layer.
Claims25
A stabilized oral pharmaceutical formulation comprising:
- a) a nucleus formed by a core;
- b) a first layer that comprises a polymer coating sealing the core and optionally one or more hydrophobic excipients;
- and
- c) a second layer coating the first layer, wherein said second layer comprises one or more labile pharmaceutically active compounds in one or more acceptable hydrophobic excipients.
1 more element
Dependencies are inferred from the claim text.