US 2004/0170678 A1 · Liposomal antineoplastic drugs and uses thereof

Abstract

This invention relates to liposomal antineoplastic agents (e.g., camptothecin) compositions and methods of using such compositions for treating neoplasia and for inhibiting angiogenesis. The compositions and methods are useful for modulating the plasma circulation half-life of an active agent.

Claims21

Dependent claims

A liposomal formulation comprising:

a) a liposome having an active agent encapsulated therein;
and
b) an empty liposome.

Dependencies are inferred from the claim text.

Facts

Application

10/788,649Filed 27 Feb 2004

Priority

30 Jun 2000

Published

2 Sep 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/1272
Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers: comprising non-phosphatidyl surfactants as…
A61K 9/1278
Preparation processes; Proliposomes: post-loading, e.g. by ion or pH gradient
A61K 31/4745
Ortho- or peri-condensed with heterocyclic ring systems: condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Family

Application60/215,556Us provisional application · filed 30 Jun 2000

Application60/264,616Us provisional application · filed 26 Jan 2001

Application09/896,812Division · filed 29 Jun 2001

Application10/788,649Division · filed 27 Feb 2004

US 2002/0110586 A1Published application

US 7,244,448 B2Related patent

US 2004/0170678 A1This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

10/788,649Filed 27 Feb 2004

Priority

30 Jun 2000

Published

2 Sep 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/1272
Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers: comprising non-phosphatidyl surfactants as…
A61K 9/1278
Preparation processes; Proliposomes: post-loading, e.g. by ion or pH gradient
A61K 31/4745
Ortho- or peri-condensed with heterocyclic ring systems: condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Family

Application60/215,556Us provisional application · filed 30 Jun 2000

Application60/264,616Us provisional application · filed 26 Jan 2001

Application09/896,812Division · filed 29 Jun 2001

Application10/788,649Division · filed 27 Feb 2004

US 2002/0110586 A1Published application

US 7,244,448 B2Related patent

US 2004/0170678 A1This patent

From the US filing history. Foreign family members aren’t listed.

Liposomal antineoplastic drugs and uses thereof

Life of this patent

Abstract

Claims21

Liposomal antineoplastic drugs and uses thereof

Life of this patent

Abstract

Claims21