Injectable polysaccharide-cell compositions
AssigneesMassachusetts Institute of Technology, Children's Medical Center Corporation
InventorsLinda G. Griffith, Anthony Atala, Charles A. Vacanti, Keith T. Paige
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Abstract
Slowly polymerizing polysaccharide hydrogels have been demonstrated to be useful as a means of delivering large numbers of isolated cells via injection. The gels promote engraftment and provide three dimensional templates for new cell growth. The resulting tissue is similar in composition and histology to naturally occurring tissue. This method can be used for a variety of reconstructive procedures, including custom molding of cell implants to reconstruct three dimensional tissue defects, as well as implantation of tissues generally.
Claims18
A method for implanting tissue into an animal comprising
- mixing a biodegradable, biocompatible hydrogel solution with dissociated cells and implanting the mixture into the animal.
A composition for implanting tissue into an animal comprising
- a hydrogel solution mixed with dissociated cells.
Dependencies are inferred from the claim text.