Use of the slug gene as a genetic marker in functions mediated by SCF (stem cell factor) and applications
OwnerIsidro Sanchez Garcia, Jesus Perez Losadainventors
Life of this patent
Estimating the term…
Abstract
The Slug gene mediates the functions of SCF linking and its c-kit receptor which means that the Slug gene, the Slug gene's CDNA, Slug protein and/or drugs or substances that activate the expression of the Slug gene can be used as therapeutic agents in the mobilization of hematopoyetic stem cells for transplants or gene therapy, in the ex vivo expansion of hematopoyetic stem cells and/or in the treatment of masculine sterility problems.
Claims7
A pharmaceutical composition that comprises the Slug gene, the complementary DNA to the RNA that codes for the product of transcription or expression of the said Slug gene (CDNA), the Slug protein and/or one or more drugs or substances that activate the expression of the Slug gene, along with one or more pharmaceutically acceptable excipients.
Use of the Slug gene, the complementary DNA that codes for the product of transcription or expression of the said Slug gene (CDNA), the Slug protein and/or one or more drugs or substances that activate the expression of the Slug gene to prepare a pharmaceutical composition to mobilize hematopoyetic stem cells for transplants or gene therapy.
Use of the Slug gene, the complementary DNA that codes for the product of transcription or expression of the said Slug gene (CDNA), the Slug protein and/or one or more drugs or substances that activate the expression of the Slug gene to prepare a pharmaceutical composition to treat masculine sterility.
A method for the ex vivo expansion of hematopoyetic stem cells involving the use of the Slug gene, the RNA that codes for the product of transcription or expression of the said Slug gene (CDNA), Slug protein and/or drugs or substances that activate the expression of the Slug gene.
Dependencies are inferred from the claim text.