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US 2004/0170603 A1Published application
Method of imaging cell death in vivo
AssigneesThe Board of Trustees of the Leland Stanford Junior University, Theseus Imaging Corporation
InventorsH. William Strauss, Francis G. Blankenberg, Allan M. Green, Neil Steinmetz
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Abstract
A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. Methods for tumor radiotherapy are also provided.
Claims21
A composition comprising an annexin or a fragment thereof coupled with a toxin.
A method of tumor therapy comprising administering to a mammalian subject having a tumor involving a nucleated cell an effective tumor reducing amount of a composition comprising an annexin or a fragment thereof coupled with a toxin.
A method of tumor therapy, comprising
- treating a subject having a tumor involving a nucleated cell with a chemotherapeutic agent;
- and
- administering to the treated subject an effective tumor reducing amount of a composition comprising an annexin or fragment thereof coupled with a toxin.
Dependencies are inferred from the claim text.