Multiplexed, absorbance-based capillary electrophoresis system and method
AssigneeCombisep, Inc.
InventorsKevin C. Kennedy, Thomas J. Kurt
Life of this patent
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Abstract
A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on-axis with and parallel to the planar array of capillary tubes. Other embodiments include vacuum use attached to the capillary tubes to increase the speed of detection.
Claims8
A reservoir manifold for a multiplexed capillary electrophoresis system, comprising:
- an acid resistant housing structure;
- a cavity disposed within said housing structure for retaining a buffer solution;
- a plurality of apertures in said housing structure for receiving capillary tubes to contact the buffer;
- at least one aperture in the housing structure for receiving an electrode to contact the buffer;
- and
- at least one other aperture for venting the cavity.
A reservoir manifold system for use in multiplexed capillary electrophoresis, comprising:
- a reservoir manifold having a cavity within itself for retaining a buffer solution, a plurality of apertures for accessing said cavity for receiving capillary tubes to contact the buffer solution within the cavity, an aperture for accessing said cavity for receiving an electrode to contact the buffer solution within the cavity and an aperture for venting the cavity;
- an electrode extending into the cavity;
- end caps that fit into each end of the cavity;
- and
- a plurality of capillary tubes extending into the cavity.
In a multiplexed capillary electrophoresis system, the improvement comprising:
- a reservoir manifold having a cavity within itself for retaining a buffer solution, a plurality of apertures for accessing said cavity for receiving capillary tubes to contact the buffer solution within the cavity, an aperture for accessing said cavity for receiving an electrode to contact the buffer solution within the cavity and an aperture for venting the cavity.
Dependencies are inferred from the claim text.