Dermal patch
AssigneePower Paper Ltd.
InventorsZvi Nitzan, Yossi Gross, Daniela Mavor, Dov Tamarkin
Life of this patent
Estimating the term…
Abstract
The invention is generally directed to a kit and patch for transdermal or intradermal delivery of at least one substance into the skin. The kit includes a dermal patch having an electrochemical cell with two electrodes and a retainer for retaining a conductive fluid which further includes an active substance. The conductive fluid can be deposited on at least one of the two electrodes. Alternatively, the conductive fluid can be applied topically to the skin.
Claims61
A kit for transdermal or intradermal delivery of at least one substance, the kit comprising:
- (a) a dermal patch which comprises an electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with a skin portion of a subject;
- and
- (b) at least one retainer for retaining a conductive fluid containing a said at least one substance, said conductive fluid being for deposition on at least one of said at least two electrodes and/or topical application onto the skin portion of the subject;
- said patch being designed and configured for delivering an electric current through the skin and said conductive fluid, said electric current being for transdermal or intradermal delivery of said at least one substance.
A kit for introduction of current and/or voltage to a skin portion of a subject, the kit comprising:
- (a) a dermal patch comprising an electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and
- (b) at least one retainer for retaining a conductive fluid, said conductive fluid being for deposition on at least one of said at least two electrodes and/or for topical application onto the skin portion of the subject;
- said patch being designed and configured for delivering an electric current through the skin and said conductive fluid, said electric current being for introduction of current and/or voltage to the skin portion of the subject.
A device for introduction of current and/or voltage to a skin portion of a subject, the device comprising:
- a dermal patch comprising an electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and
- said patch being designed and configured for delivering an electric current through the skin, said electric current being for introduction of current and/or voltage to the skin portion of the subject.
A kit for treatment of hyperhidrosis, the kit comprising:
- (a) a dermal patch which comprises an electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with a skin portion of a subject;
- and
- (b) at least one retainer for retaining a conductive fluid containing at least one substance, said conductive fluid being for deposition on at least one of said at least two electrodes and/or topical application onto the skin portion of the subject;
- said patch being designed and configured for delivering an electric current through the skin and said conductive fluid, said electric current being for treatment of hyperhidrosis.
A device for introduction of water to a skin portion of a subject, the device comprising:
- a dermal patch comprising an electrochemical cell wherein said electrochemical cell is a flexible thin layer open liquid state electrochemical cell which comprises a first layer of insoluble negative pole, a second layer of insoluble positive pole and a third layer of aqueous electrolyte, said third layer being disposed between said first and second layers and including:
- (a) a deliquescent material for keeping the open cell wet at all times;
- (b) an electroactive soluble material for obtaining required ionic conductivity;
- and
- (c) a water-soluble polymer for obtaining a required viscosity for adhering said first and said second layers to said third layer, having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and said patch being designed and configured for delivering an electric current through the skin, said electric current being for introduction of water to the skin portion of the subject.
A device for treatment of hyperhidrosis, the device comprising:
- a dermal patch comprising an electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and said patch being designed and configured for delivering an electric current through the skin, said electric current being for delivery of ions into the skin portion of the subject and for treatment of hyperhidrosis.
A device for treatment of hyperhidrosis, the device comprising:
- a dermal patch comprising an electrochemical cell where in said electrochemical cell is a small and thin electrochemical cell having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and said patch being designed and configured for delivering an electric current through the skin, said electric current being for delivery of ions into the skin portion of the subject and for treatment of hyperhidrosis.
A device for treatment of hyperhidrosis, the device comprising:
- a dermal patch comprising an electrochemical cell where in said electrochemical cell is a flexible thin layer open liquid state electrochemical cell which comprises a first layer of insoluble negative pole, a second layer of insoluble positive pole and a third layer of aqueous electrolyte, said third layer being disposed between said first and second layers and including:
- (a) a deliquescent material for keeping the open cell wet at all times;
- (b) an electroactive soluble material for obtaining required ionic conductivity;
- and
- (c) a water-soluble polymer for obtaining a required viscosity for adhering said first and said second layers to said third layer,
- having at least two electrodes positioned on one side of the dermal patch, said electrodes being for forming electrical contact with the skin portion of the subject;
- and said patch being designed and configured for delivering an electric current through the skin, said electric current being for delivery of ions into the skin portion of the subject and for treatment of hyperhidrosis.
An iontophoretic patch for transdermal or intradermal delivery of at least one substance, the patch comprising:
- (a) an electrochemical cell for powering said patch;
- (b) at least two electrodes in electrical contact with said electrochemical cell;
- and
- (c) a conductive fluid, wherein said conductive fluid is preapplied to said at least two electrodes;
- and wherein on contacting said patch with skin an electric current is delivered through said conductive fluid and skin of a subject so as to transdermally or intradermally deliver said at least one substance.
An iontophoretic patch for transdermal or intradermal delivery of water, the patch comprising:
- (a) an electrochemical cell for powering said patch;
- (b) at least two electrodes in electrical contact with said electrochemical cell;
- and
- (c) an aqueous conductive fluid, wherein said aqueous conductive fluid is preapplied to said at least two electrodes;
- and wherein on contacting said patch with skin an electric current is delivered through said aqueous conductive fluid and skin of a subject so as to transdermally or intradermally deliver water from said aqueous conductive fluid.
Dependencies are inferred from the claim text.