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US 2004/0167223 A1Published application
Topical antibacterial formulations
OwnerKarl F. Poppinventor
Life of this patent
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Abstract
Methods of using a topical composition comprising a storage-stable mixture of a benzoyl peroxide dispersion and clindamycin or pharmaceutically acceptable salts or esters thereof for treating a bacterial disorder. These methods also contemplate the reduction or elimination of particular bacteria from affected skin areas, thereby reducing skin lesions or infections.
Claims63
A method for treating a bacterial disorder in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said bacterial disorder, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said bacterial disorder.
A method for reducing or eliminating bacteria from skin of a patient, comprising:
- topically administering to skin of a patient infected with said bacteria a topical composition in an amount effective to reduce or eliminate said bacteria, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in reducing or eliminating said bacteria.
A method for treating a bacterial disorder in a patient having sensitive skin, comprising:
- topically administering to sensitive skin areas of a patient in need thereof a topical composition in an amount effective to treat said bacterial disorder, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier;
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said bacterial disorder in said sensitive skin.
A method for treating a topical bacterial infection in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said topical bacterial infection, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said topical bacterial infection.
A method for treating impetigo in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said impetigo, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said impetigo.
A method for treating folliculitis in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said folliculitis, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said folliculitis.
A method for treating erythrasma in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said erythrasma, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said erythrasma.
A method for treating a bacterial disorder in skin of a patient, comprising:
- topically administering to the skin of a patient in need thereof a topical composition in an amount effective to treat said bacterial disorder, wherein said topical composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating said bacterial disorder;
- and wherein said topical composition is administered concomitantly or sequentially with an additional active agent effective to treat said bacterial disorder.
1 more element
Dependencies are inferred from the claim text.