US 2004/0167191 A1 · Glutaminyl based DPIV inhibitors

Abstract

The present invention provides compounds of the formula: 1 wherein X═CH2 or S or pharmaceutical acceptable salts thereof useful for treating conditions mediated by DPIV or DPIV-like enzymes, such as arthritis, obesity, immune and autoimmune disorders, allograft transplantation, cancer, neuronal disorders and dermal diseases.

Claims11

Dependent claims

A compound of formula:

6
wherein X═CH2 or S or an acid addition salt thereof.

Dependencies are inferred from the claim text.

Facts

Application

10/779,158Filed 13 Feb 2004

Priority

WO PCT/EP02/0712427 Jun 2002

Published

26 Aug 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification28 codes

C07D 277/04
Not condensed with other rings: having no double bonds between ring members or between ring members and non-ring members
A61K 38/04
Medicinal preparations containing peptides: peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A61K 38/06
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: tripeptides
A61K 38/07
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: tetrapeptides

Family

Application60/360,909Us provisional application · filed 28 Feb 2002

Application10/244,347Continuation · filed 16 Sep 2002

Application10/779,158Continuation · filed 13 Feb 2004

US 2003/0162820 A1Published application

US 6,946,480 B2Related patent

US 7,060,719 B2Related patent

US 2004/0167191 A1This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

10/779,158Filed 13 Feb 2004

Priority

WO PCT/EP02/0712427 Jun 2002

Published

26 Aug 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification28 codes

C07D 277/04
Not condensed with other rings: having no double bonds between ring members or between ring members and non-ring members
A61K 38/04
Medicinal preparations containing peptides: peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A61K 38/06
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: tripeptides
A61K 38/07
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: tetrapeptides

Family

Application60/360,909Us provisional application · filed 28 Feb 2002

Application10/244,347Continuation · filed 16 Sep 2002

Application10/779,158Continuation · filed 13 Feb 2004

US 2003/0162820 A1Published application

US 6,946,480 B2Related patent

US 7,060,719 B2Related patent

US 2004/0167191 A1This patent

From the US filing history. Foreign family members aren’t listed.

Glutaminyl based DPIV inhibitors

Life of this patent

Abstract

Claims11

Glutaminyl based DPIV inhibitors

Life of this patent

Abstract

Claims11