Methods of preventing breast cancer

A method for preventing breast cancer in a post-menopausal human female which comprises administering to said post-menopausal human female for a sufficient term an effective dose of a compound of the formula

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• or a pharmaceutically acceptable salt or solvate thereof.

A method for preventing breast cancer comprising administrating to a human for a sufficient term an effective dose of a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof, said human being at no particular risk of developing breast cancer.

An article of manufacture comprising packaging material and a pharmaceutical agent contained within said packaging material, wherein said packaging material comprises a label which indicates said pharmaceutical agent may be administered, for a sufficient term at an effective dose, for preventing breast cancer in a human and wherein said pharmaceutical agent is a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof.

An article of manufacture comprising packaging material and a pharmaceutical agent contained within said packaging material, wherein said packaging material comprises a label which indicates said pharmaceutical agent may be administered, for a sufficient term and at an effective dose, for preventing breast cancer in a post-menopausal human female wherein said pharmaceutical agent is a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof.

An article of manufacture comprising packaging material and a pharmaceutical agent contained within said packaging material, wherein said packaging material comprises a label which indicates said pharmaceutical agent may be administered, for a sufficient term at an effective dose, for preventing breast cancer in a human at no particular risk of developing breast cancer wherein said pharmaceutical agent is a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof.

The use of a compound of the formula

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• or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament for preventing breast cancer in a human, said medicament to be administered to said human for a sufficient term and at an effective dose.

The use of a compound of the formula

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• or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament for preventing breast cancer in a post-menopausal human female, said medicament to be administered to said post-menopausal human female for a sufficient term and at an effective dose.

The use of a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament for preventing breast cancer in a human being at no particular risk of developing breast cancer, said medicament to be administered to said human for a sufficient term and at an effective dose.

A pharmaceutical formulation comprising as an active ingredient a compound of the formula

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• or a pharmaceutically acceptable salt or solvate thereof, said pharmaceutical formulation adapted for preventing breast cancer in a human by administration for a sufficient term an effective dose of said compound to said human.

A pharmaceutical formulation comprising as an active ingredient a compound of the formula

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• or a pharmaceutically acceptable salt or solvate thereof, said pharmaceutical formulation adapted for preventing breast cancer in a post-menopausal human female by administration for a sufficient term an effective dose of said compound to said human.

A pharmaceutical formulation comprising as an active ingredient a compound of formula I

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• or a pharmaceutically acceptable salt or solvate thereof, said pharmaceutical formulation adapted to prevent breast cancer in a human being at no particular risk of developing breast cancer, by administration for a sufficient term an effective dose of said compound to said human.