Back to results
US 2004/0167089 A1Published application
Immunostimulatory nucleic acid molecules
AssigneesUniversity of Iowa Research Foundation, Coley Pharmacuetical Group, Inc., The USA, as represented by the Secretary, Dept. of Health and Human Services
InventorsArthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
Life of this patent
Estimating the term…
Abstract
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
Claims18
A method for treating an atopic condition, comprising
- administering to a subject in need of treatment of an atopic condition an immunostimulatory nucleic acid, comprising:
- 5′ X1CGX2 3′
- wherein the immunostimulatory nucleic acid includes at least 8 nucleotides and wherein C is unmethylated and wherein X1 and X2 are nucleotides, in an effective amount to treat the atopic condition.
Dependencies are inferred from the claim text.