C3A serum-free clonal cell line and methods of use
AssigneeVital Therapies, Inc.
InventorsDennis Triglia, Anthony Purchio
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Abstract
A serum-free C3A clonal cell line and methods for generating the same are provided. The C3A cell line has a reduced doubling time in serum-free medium compared to a corresponding C3A cell line from which it is derived. Methods using the cells of the serum-free C3A clonal cell line for the production, expression and recovery of harvestable polypeptides, screening compounds for metabolic activity, studying enteric disease and for use in a bio-artificial liver device are also provided.
Claims28
A C3A clonal cell line derived from a parental C3A cell line, wherein said clonal cell line has a doubling time in serum-free medium significantly less than the doubling time of said parental line in said serum-free medium.
Dependencies are inferred from the claim text.