US 2004/0166500 A1 · Secretory molecules

Secretory molecules

OwnerScott R Panzer, Stephen E Lincoln +16inventors

InventorsScott R Panzer, Stephen E Lincoln, Christina M Altus, Gerard E Dufour, Jennifer L Jackson, Anissa L Jones, Tam C Dam, Tommy F Liu, Bernard Harris, Vincent Z Flores, Abel Daffo, Rakesh Marwaha, Alice J Chen, Simon C Chang, Edward H Gerstin Jr, Careyna H Peralta, Marie H David, Samantha A Lewis

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Abstract

The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.

Claims28

Dependent claims

An isolated polynucleotide selected from the group consisting of:

a) a polynucleotide comprising a polynucleotide sequence selected from the group consisting of NO:1-75,
b) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to a polynucleotide sequence selected from the group consisting of NO:1-75,
c) a polynucleotide complementary to the polynucleotide of a),
d) a polynucleotide complementary to the polynucleotide of b), and
e) an RNA equivalent of a)-d).

2 more elements

Dependencies are inferred from the claim text.