Fluid-jet pens configured for making modulated release bioactive agents
OwnerJohn Stephen Dunfield, James W. Ayresinventors
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Abstract
The present invention is drawn to methods of preparing a bioactive agent-containing emulsion for delivery to a biological system. This method can comprise the step of jetting a bioactive agent and a first fluid medium from a fluid-jet pen into a second fluid medium to form a bioactive agent-containing emulsion, wherein the second fluid comprises a continuous phase of the emulsion. Alternatively, a method of preparing a bioactive agent-containing liposome can comprise jetting a lipid-containing composition and a bioactive agent from a fluid-jet pen into a medium to form a bioactive agent-containing liposome carried by the medium.
Claims50
A method of preparing a bioactive agent-containing emulsion for delivery to a biological system, comprising jetting:
- (a) a bioactive agent, and
- (b) a first fluid medium, from a fluid-jet pen into a second fluid medium to form a bioactive agent-containing emulsion, wherein the second fluid comprises a continuous phase of the emulsion.
A method of preparing a bioactive agent-containing liposome, comprising jetting:
- (a) a lipid-containing composition, and
- (b) a bioactive agent, from a fluid-jet pen into a carrier medium to form a bioactive agent-containing liposome carried by the carrier medium.
A bioactive agent release system, comprising a fluid-jet pen containing:
- (a) a bioactive agent;
- and
- (b) a release agent,
- wherein the fluid-jet pen is configured for jetting the bioactive agent and the release agent, resulting in an association between the bioactive agent and the release agent.
Dependencies are inferred from the claim text.