Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine
AssigneePepscan Systems B.V.
InventorsRobert Hans Meloen, Hendrica Berendina Oonk
Life of this patent
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Abstract
A peptide that comprises a modified tandem GnRH decapeptide sequence which allows for a testosterone level that is essentially nondetectable after vaccination with the peptide in a suitable dosage and/or allows for an immunogenic response that allows for the effective discrimination between GnRH-I and GnRH-II and a method for the immunocastration of pigs.
Claims50
A peptide comprising a modified tandem GnRH decapeptide sequence capable of inducing an immunogenic response that allows for discrimination between different types of GnRH.
A peptide comprising a modified tandem GnRH decapeptide sequence which allows for a testosterone level that is essentially nondetectable after vaccination with the peptide in a suitable dosage.
A method for the treatment of prostate cancer comprising administration of a suitable dose of a composition comprising a peptide that elicits at least an immunogenic response against GnRH-II.
Dependencies are inferred from the claim text.