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US 2004/0166090 A1Published application
Compositions comprising oestrone-3-0-sulphamate and trail (TNF-related apoptosis inducing ligand)
AssigneeSterix Limited
InventorsKeith Graham Packham, Michael John Reed, Barry Victor Lloyd Potter
Life of this patent
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Abstract
The present invention provides a composition comprising (i) a compound comprising a sulphamate group (“a sulphamate compound”); and (ii) an apoptosis inducer.
Claims43
A composition comprising
- i) a sulphamate compound having a sulphamate group;
- and
- ii) an apoptosis inducer.
A method of upregulating receptor function of a tumour necrosis factor apoptosis inducing ligand (TRAIL) receptor, the method comprising contacting a cell comprising the TRAIL receptor with a sulphamate compound.
A method of activating a caspase comprising contacting a cell comprising caspase with a sulphamate compound.
Dependencies are inferred from the claim text.