Systems and methods for global optimization of treatment planning for external beam radiation therapy
AssigneeGeorgia Tech Research Corporation
InventorEva K. Lee
Life of this patent
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Abstract
Systems and methods for providing an optimal treatment plan for delivering a prescribed radiation dose to a predefined target volume within a patient using an external beam radiation delivery unit are provided. One such method comprises: (1) receiving information related to the prescribed radiation dose, the predefined target volume, and parameters associated with the external beam delivery unit, (2) developing a treatment plan optimization model based on a plurality of variables corresponding to the information which define a global system, and (3) outputting an optimal treatment plan based on the treatment plan optimization model and the information.
Claims26
A method for developing an optimal treatment plan for treatment of a target volume within a patient using an external beam radiation delivery unit, the method comprising:
- receiving information corresponding to at least one parameter related to intensity-modulated radiation therapy (IMRT) to be used in developing the optimal treatment plan;
- receiving information corresponding to at least one clinical objective related to a target volume and a critical structure;
- developing a treatment plan optimization model based on a plurality of variables corresponding to the at least one parameter related to IMRT and the at least one clinical objective which define a global system;
- and
- developing a globally optimal treatment plan which optimizes the at least one clinical objective subject to the at least one parameter.
A system for optimizing treatment planning in intensity-modulation radiation therapy (IMRT), the system comprising:
- a user interface for enabling a user to specify at least one parameter related to IMRT, at least one constraint, and at least one clinical objective;
- a treatment plan modeling module configured to develop a treatment plan optimization model containing a plurality of variables corresponding to the at least one parameter related to IMRT, the at least one constraint, and the at least one clinical objective;
- and
- a global optimization module configured to calculate a globally optimal treatment plan which optimizes the at least one clinical objective subject to the at least one parameter related to IMRT and the at least one constraint.
A system for optimizing treatment planning in intensity-modulation radiation therapy (IMRT), the system comprising:
- means for interfacing with an I/O device to enable a user to specify at least one parameter related to IMRT, at least one constraint, and at least one clinical objective;
- means for modeling a global system based on a plurality of variables corresponding to the at least one parameter related to IMRT, the at least one constraint, and the at least one clinical objective;
- and
- means for calculating a globally optimal treatment plan which optimizes the at least one clinical objective subject to the at least one parameter related to IMRT and the at least one constraint.
A computer program embodied in a computer-readable medium for optimizing treatment planning in intensity-modulation radiation therapy (IMRT), the computer program comprising:
- logic configured to interface with a user and enable the user to specify at least one parameter related to IMRT, at least one constraint, and at least one clinical objective;
- logic configured to develop a treatment plan optimization model containing a plurality of variables corresponding to the at least one parameter related to IMRT, the at least one constraint, and the at least one clinical objective;
- and
- logic configured to calculate a globally optimal treatment plan which optimizes the at least one clinical objective subject to the at least one parameter related to IMRT and the at least one constraint.
Dependencies are inferred from the claim text.