Novel elongase gene and method for producing multiple-unsaturated fatty acids
AssigneeBASF SE
InventorsErnst Heinz, Thorsten Zank, Ulrich Zahringer, Jens Lerchl, Andreas Renz
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AssigneeBASF SE
InventorsErnst Heinz, Thorsten Zank, Ulrich Zahringer, Jens Lerchl, Andreas Renz
Estimating the term…
The invention relates to a novel elongase gene with the sequences stated in sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or their homologs, derivatives or analogs, to a gene construct comprising this gene or its homologs, derivatives and analogs, and to its use. The invention also relates to vectors or transgenic organisms comprising an elongase gene with the sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or its homologs, derivatives and analogs. The invention furthermore relates to the use of the elongase gene sequences alone or in combination with further elongases and/or further fatty acid biosynthesis genes. The present invention relates to a novel elongase gene with the sequence SEQ ID NO:1 or its homologs, derivatives and analogs. Furthermore, the invention relates to a process for the preparation of polyunsaturated fatty acids and to a process for introducing DNA into organisms which produce large amounts of oils and, in particular, oils with a high content of unsaturated fatty acids. Moreover, the invention relates to an oil and/or a fatty acid preparation with a higher content of polyunsaturated fatty acids with at least two double bonds and/or a triacylglycerol preparation with a higher content of polyunsaturated fatty acids with at least two double bonds.
An isolated nucleic acid derived from a plant or alga and encoding a polypeptide which elongates C16, C18- or C20-fatty acids with at least two double bonds in the fatty acid by at least two carbon atoms.
An isolated nucleic acid encompassing a nucleotide sequence encoding a polypeptide which elongates C16-, C18- or C20-fatty acids with at least two double bonds in the fatty acid molecule, selected from the group consisting of
An oil, lipid or fatty acid composition which comprises PUFAs and which is derived from a transgenic plant.
A composition, comprising the antibody as claimed in claim 14, the antisense nucleic acid construct as claimed in claim 15 or an antagonist or agonist identified as claimed in claim 28.
A kit, comprising the nucleic acid as claimed in any of claims 1 to 4, the gene construct as claimed in any of claims 5 to 8, the antisense nucleic acid molecule as claimed in claim 15, the antibody as claimed in claim 14, an antagonist or agonist identified as claimed in claim 28, the composition as claimed in claim 26, the amino acid sequence as claimed in claim 9 and/or oil, lipids and/or fatty acids or a fraction thereof as claimed in any of claims 22 to 25.
A process for identifying an antagonist or agonist of elongases, comprising
Dependencies are inferred from the claim text.