Mammalian cancer cell and transgenic mammal carrying human protooncogene and kit for diagnosing cancer using said protooncogene
OwnerJin-Woo Kiminventor
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Abstract
The present invention provides a mammalian cell transfected with an expression vector comprising a human protooncogene which has the nucleotide sequence of SEQ ID NO: 1; a mammalian embryo carrying a nucleic acid construct comprising the human protooncogene; a transgenic cancered mammal, which is derived from the mammalian embryo; and a kit for diagnosing a cancer selected from the group consisting of breast, kidney, ovary and stomach cancers, which comprises a probe having the nucleotide sequence complementary to mRNA transcribed from the human protooncogene or a portion of the mRNA; or an antibody binding specifically to a protein translated from the mRNA or a portion of the protein.
Claims8
A mammalian cell transformed with an expression vector comprising a human protooncogene which has the nucleotide sequence of SEQ ID NO:
- 1.
A mammalian embryo carrying an introduced nucleic acid construct comprising a human protooncogene which has the nucleotide sequence of SEQ ID NO:
- 1.
A kit for diagnosing a cancer selected from the group consisting of breast, kidney, ovary and stomach cancers, which comprises a probe having the nucleotide sequence complementary to mRNA transcribed from the human protooncogene having the nucleotide sequence of SEQ ID NO:
- 1 or a portion of the mRNA;
- or an antibody binding specifically to a protein translated from the mRNA or a portion of the protein.
Dependencies are inferred from the claim text.