Human IRAK-2
AssigneesHuman Genome Sciences, Inc., The Regents of the University of Michigan
InventorsJian Ni, Ping Feng, Marta Muzio, Vishva M. Dixit
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Abstract
The present invention relates to a novel IRAK-2 protein which is a member of the IL-1 signaling pathway. In particular, isolated nucleic acid molecules are provided encoding the human IRAK-2 protein. IRAK-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for detecting IRAK-2 related disorders and therapeutic methods for treating IRAK-2 related disorders.
Claims15
An isolated nucleic acid molecule comprising a polynucleotide at least 95% identical to a nucleotide sequence encoding amino acids 1 to 96 of SEQ ID NO:2.
An isolated polypeptide comprising an amino acid sequence at least 95% identical to amino acids 1 to 96 of SEQ ID NO:2.
Dependencies are inferred from the claim text.