Loading patent…
AssigneeTakeda Pharmaceutical Company Limited
InventorsSyuji Sato, Yasushi Shintani, Nobuyuki Miyajima, Koji Yoshimura
Estimating the term…
The present invention aims at providing a useful and novel G protein-coupled receptor protein and DNA thereof. The G protein-coupled receptor protein of the present invention and the like, and the polynucleotides encoding the receptor protein and the like, are useful for; 1) determination of ligands (agonists); 2) preparation of antibodies and antisera; 3) construction of recombinant receptor protein expression systems; 4) development of the receptor binding assay systems using the expression systems and screening of pharmaceutical candidate compounds; 5) effecting drug design based on comparison with structurally similar ligand receptors; 6) reagents for preparation of probes and PCR primers for gene diagnosis; 7) production of transgenic animals; and 8) pharmaceutical drugs for the gene prophylaxis and gene therapy.
A G protein-coupled receptor protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO:
A G protein-coupled receptor protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO:
A G protein-coupled receptor protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO:
A diagnostic product, which comprises combining a polynucleotide containing a polynucleotide containing a base sequence represented by SEQ ID NO:
A diagnostic method, which comprises measuring an expression level of the G protein coupled receptor protein containing an amino acid sequence represented by SEQ ID NO:
A diagnostic method, which comprises measuring an expression level of (i) the G protein coupled receptor protein containing an amino acid sequence represented by SEQ ID NO:
A diagnostic method, which comprises measuring an expression level of (i) the G protein coupled receptor protein containing an amino acid sequence represented by SEQ ID NO:
Dependencies are inferred from the claim text.