Novel protein having hemolytic activity and gene encoding the protein

Abstract

Novel proteins having hemolytic activity giving the new approach of development of the drugs, and having the following property are provided: (1) having hemolytic activity; (2) having a molecular weight of about 50,000 Da (determined by SDS gel electrophoresis); and (3) having an amino acid sequence represented by any of SEQ ID NO 1 and SEQ ID NO 2 as a partial amino acid sequence represented by the following amino acid sequences (1) and (2); Amino acid sequence (1): Tyr-Arg-Asp-Gln-Glu-Leu-Glu-Asp-Asn-Val-Lys Amino acid sequence (2): Lys-Trp-Pro-Asp-Tyr-Phe-Val-Tyr-Met-Glu-Ser-Ser-Ala-His-Gly-Tyr-Ile-Arg (wherein, an amino acidresidue is written by the 3 letters notation defined by IUPAC and IUB) obtained from nematocyst of Carybdea alata.

Dependencies are inferred from the claim text.