Compounds extracted from Sap of Rhus succedanea
OwnerPei-Lin Wu, Shwu-Bin Lin +1inventors
InventorsPei-Lin Wu, Shwu-Bin Lin, Robin Yih-Yuan Chiou
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Abstract
The present invention relates to new antioxidative and cytotoxic hydroquinone compounds 10′(Z),13′(E),15′(E)-heptadecatrienylhydroquinone (1) and 10′(Z),13′(E)-heptadecadienylhydroquinone (2) that were mainly isolated from an ethanol extract of the sap of Rhus succedanea. The structures of these compounds were determined by spectral analyses and showed potent antioxidative activity and cytotoxicity against human cancer cells. This invention also includes anti-tumor pharmaceutical composition of the hydroquinone compounds.
Claims11
A hydroquinone compound substantially having the general formula of:
- 1
- wherein r is 10′(Z),13′(E),15′ (E)-heptadecatrienyl or 10′(Z),13′(E)-heptadecadienyl, and a pharmaceutically acceptable salt or ester thereof.
Dependencies are inferred from the claim text.