Antisense modulatin of talin expression
OwnerC Frank Bennett, Lex M Cowsertinventors
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of Talin. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Talin. Methods of using these compounds for modulation of Talin expression and for treatment of diseases associated with expression of Talin are provided.
Claims20
An antisense compound 8 to 30 nucleobases in length targeted to the 5′-untranslated region, coding region, stop codon or 3′ untranslated region of a nucleic acid molecule encoding human Talin, wherein said antisense compound specifically hybridizes with and inhibits the expression of human Talin.
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