Carrier system for cyclosporin pharmaceutical compositions
OwnerEdwards E. Linninventor
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Abstract
A homogeneous cyclosporin composition containing a pharmaceutically effective amount of cyclosporin in association with a pharmaceutical carrier, said carrier comprising a drug solubilizing effective amount of mono or diester of propylene glycol of lauric acid with monoester content of at least 90% by weight, a non-ionic surfactant and a dispersing agent. The composition described herein provides greater solubility of cyclosporin and cyclosporin capsule shell stability.
Claims12
A pharmaceutical composition comprising a pharmaceutically effective amount of cyclosporin in a carrier vehicle, said carrier vehicle including at least a mono/diester of propylene glycol lauric acid in which the monoester content is at least 90% by weight, a non-ionic surfactant having HLB value of greater than 10, and a dispersing agent.
Dependencies are inferred from the claim text.