Rapidly disintegrating tablet comprising an acid-labile active ingredient
AssigneeAltana Pharma AG
InventorsRango Dietrich, Hartmut Ney, Rudolf Linder
Life of this patent
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Abstract
A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
Claims10
A rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprising a plurality of individual active ingredient units together with one or more pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
A rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprising a plurality of individual active ingredient units together with one or more pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units i) in a matrix composed of a mixture comprising at least one fatty alcohol and at least one solid paraffin, ii) in a matrix composed of a mixture comprising at least one triglyceride and at least one solid paraffin or iii) in a matrix composed of a mixture comprising at least one fatty acid ester and at least one solid paraffin, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
Dependencies are inferred from the claim text.