Back to results
US 2004/0106868 A1Published application
Novel imaging markers in musculoskeletal disease
OwnerSiau-Way Liew, Konstantinos Tsougarakis +4inventors
InventorsSiau-Way Liew, Konstantinos Tsougarakis, Claude D. Arnaud, Philipp Lang, Daniel Steines, Barry J. Linder
Life of this patent
Estimating the term…
Abstract
This invention is directed to methods for using imaging methods to aid in drug discovery, and drug development. This invention also relates to methods of using imaging methods for diagnosis, prognostication, monitoring and patient management of musculoskeletal disease.
Claims88
A method for analyzing at least one of bone mineral density, bone structure and surrounding tissue comprising:
- a. obtaining an image of a subject;
- b. locating a region of interest on the image;
- c. obtaining data from the region of interest;
- and
- d. deriving data selected from the group of qualitative and quantitative from the image data obtained at step c.
2 more elements
A kit for aiding in the assessment of the condition of at least one of a bone and joint comprising:
- a software program which reads at least one of a degeneration pattern, a pattern of normal tissue, a pattern of abnormal tissue, and a pattern of diseased tissue.
An automated method of using an imaging marker comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- administering an agent.
1 more element
A semi-automated method of using an imaging marker comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- administering an agent.
1 more element
A system for monitoring the efficacy of an agent comprising:
- administering an agent to a subject;
- obtaining image data;
- and
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data.
1 more element
A system for drug discovery comprising:
- administering an agent to a subject;
- obtaining image data;
- and
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data.
1 more element
A system for diagnosing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for diagnosing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for diagnosing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for determining disease staging comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for determining disease staging comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for determining disease staging comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for monitoring disease progression comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for monitoring disease progression comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for monitoring disease progression comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for managing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for managing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for managing a disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for disease prognostication comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for disease prognostication comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for disease prognostication comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for predicting disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for predicting disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for predicting disease comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for monitoring therapy comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for monitoring therapy comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for monitoring therapy comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
A system for randomizing a group of patients comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a database of at least quantitative and qualitative data obtained from a group of subjects.
1 more element
A system for randomizing a group of patients comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time T1.
1 more element
A system for randomizing a group of patients comprising:
- obtaining image data;
- obtaining data from the image data wherein the data obtained is at least one of quantitative and qualitative data;
- and
- comparing the at least one of quantitative and qualitative data to a at least one of quantitative and qualitative data obtained from the subject at time Tn.
1 more element
Dependencies are inferred from the claim text.