Processes for the preparation of oxo-oxazoline or alloamino acid derivatives
AssigneeShionogi & Co., Ltd.
InventorsMakoto Kobayashi, Haruo Koike, Masahiko Nagai
Life of this patent
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Abstract
A method for producing a compound represented by the general formula (I-A) or the general formula (I-B), comprising the following step: 1 wherein R1 is an optionally substituted lower alkyl, and the like; R2 is a lower alkyl or an optionally substituted aralkyl, and the like; R3 is a lower alkyl, characterized in that a compound represented by the general formula (II-A) or the general formula (II-B) is treated with thionyl chloride.
Claims11
A method for production of a compound represented by the general formula (I-A) or the general formula (I-B), comprising the step of treating a compound represented by the general formula (II-A) or the general formula (II-B) with thionyl chloride as follows:
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- wherein R1 is an optionally substituted lower alkyl, an optionally substituted aryl, an alkynyl, or an optionally substituted heteroaryl;
- R2 is a lower alkyl, an optionally substituted aralkyl, or an optionally substituted heteroarylalkyl;
- and R3 is a lower alkyl.
A method for production of a compound represented by the general formula (I-A) or the general formula (I-B), comprising the step of protecting the amino group of a compound represented by the general formula (V-A) or the general formula (V-B) with R2OC(═O)—, wherein R2 is as described above, esterifying the carboxyl group thereof, and treating with thionyl chloride as follows:
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- wherein R1 and R3 are as described above.
Dependencies are inferred from the claim text.