Compositions for the parenteral administration of calcium and magnesium
OwnerThomas A. Dobbins, David B. Wiley +1inventors
InventorsThomas A. Dobbins, David B. Wiley, Michael Davis
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Abstract
Aqueous solutions of the calcium and/or magnesium salts of 3-hydroxy-3-methylbutyric acid are useful for parenteral administration of the calcium and/or magnesium in the treatment and prevention of disorders caused by or accompanied by hypocalcemia or hypomagnesia.
Claims39
A method for elevating blood serum levels of calcium and/or magnesium cations in a human or other animal subject in need thereof comprising:
- parenterally administering a safe and effective amount of a composition comprising at least one salt selected from the group consisting of calcium 3-hydroxy-3-methylbutyrate and magnesium 3-hydroxy-3-methylbutyrate to said subject.
A method for preventing and/or treating a condition associated with calcium and/or magnesium deficiency in a human or other animal subject comprising parenterally administering to said subject a safe and effective amount of a composition comprising at least one salt selected from the group consisting of calcium 3-hydroxy-3-methylbutyrate and magnesium 3-hydroxy-3-methylbutyrate.
A composition for elevating blood serum levels of alkaline earth metal cations in a human or other animal subject in need thereof comprising:
- (a) an alkaline earth metal component,
- (b) a biocompatible organic acid component, and
- (c) a sterile aqueous solution selected from the group consisting of normal saline, lactated ringers, and 5% dextrose in water,
- wherein said alkaline earth metal is selected from the group consisting of calcium, magnesium, and mixtures thereof, and said biocompatible organic acid comprises 3-hydroxy-3-methylbutyric acid,
- wherein said composition is suitable for parenteral administration to said subject.
Dependencies are inferred from the claim text.