Compositions and methods for inhibiting proliferation in human prostate cancer cells
OwnerAllan H. Conneyinventor
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Abstract
The present invention includes compositions and methods for treatment of prostate cancer which involve the use of 12-O-tetradecanoylphorbol-13-acetate combined with a retinoid such as all-trans-retinoic acid or paclitaxol, wherein the drugs are administered together, and further wherein the combined use of these agents results in a synergistic effect on prostate tumor cell growth.
Claims8
A composition for inhibition of prostate tumor cell growth comprising 12-O-tetradecanoylphorbol-13-acetate and a retinoid administered together or separately in pharmaceutically acceptable carriers or diluents.
A composition for treatment of prostate cancer in a human comprising 12-O-tetradecanoylphorbol-13-acetate and a retinoid administered together or separately in pharmaceutically acceptable carriers or diluents.
A composition for inhibition of prostate tumor cell growth comprising 12-O-tetradecanoylphorbol-13-acetate and paclitaxol administered together or separately in pharmaceutically acceptable carriers or diluents.
A composition for treatment of prostate cancer in a human comprising 12-O-tetradecanoylphorbol-13-acetate and paclitaxol administered together or separately in pharmaceutically acceptable carriers or diluents.
Dependencies are inferred from the claim text.