Chelation of charged and uncharged molecules with porphyrin-based compounds
AssigneeBoard of Supervisors of Louisiana State University and Agricultural and Mechanical College
InventorMaria da Graca Henriques Vicente
Life of this patent
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Abstract
Porphyrins containing one or more neutral or negatively-charged, closo- or nido-carborane substituents are useful as chelators. The carbon-carbon bonds linking the boron-containing groups to the porphyrin ring make the compounds highly resistant to hydrolysis. These compounds have potential for use in selective binding to specific ligands. These compounds are highly stable, soluble in water and organic solvents, and have low toxicity.
Claims18
A method for selectively binding a neutral, positively-charged, or negatively-charged molecule, in solution or in the solid state, said method comprising contacting the molecule with a compound comprising a porphyrin macrocycle, and further comprising one or more carboranyl groups that are linked to the porphyrin macrocycle by carbon-carbon bonding.
Dependencies are inferred from the claim text.