US 2004/0106591 A1 · Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia

Abstract

Compositions for treating or preventing fat maldistribution or hyperlipidemia resulting from anti-retroviral treatment of HIV-1 infection are disclosed. The compositions contain a conjugated fatty acid or alcohol and at least one member selected from the group consisting of a thiol-containing compound and a bioavailable form of trivalent chromium. Methods of treating a subject suffering from HIV-associated fat maldistribution or hyperlipidemia by administering a composition that includes a conjugated fatty acid or conjugated fatty alcohol and at least one member selected from the group consisting of a thiol-containing compound and a bioavailable form of trivalent chromium are similarly provided.

Claims40

Dependent claims

A composition for treating, preventing or normalizing fat maldistribution resulting from anti-retroviral treatment of HIV-1 infection, said composition comprising a conjugated fatty acid or conjugated fatty alcohol and at least one member selected from the group consisting of thiol-containing compounds and bioavailable forms of trivalent chromium.

Dependencies are inferred from the claim text.

Facts

Application

10/699,195Filed 31 Oct 2003

Priority

22 Nov 2002

Published

3 Jun 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

A61K 31/28
Medicinal preparations containing organic active ingredients: compounds containing heavy metals
A61K 31/045
Medicinal preparations containing organic active ingredients: hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/198
The amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine,…:…
A61K 31/20
Carboxylic acids, e.g. valproic acid: having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids

Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia

Life of this patent

Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia

Life of this patent

Abstract

Claims40