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US 2004/0106589 A1Published application
Fatty acid-pharmaceutical agent conjugates
AssigneeProtarga Pharmaceuticals, Inc.
InventorsNigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
Life of this patent
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Abstract
The invention provides conjugates of fatty acids and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
Claims12
A method for targeting a pharmaceutical agent to a noncentral nervous system tissue to treat a noncentral nervous system condition comprising:
- administering to a subject in need of such treatment a covalent conjugate of a C8-26, unbranched, naturally occurring fatty acid and a pharmaceutical agent effective for treating said condition provided that the drug is not an adenosine receptor agonist or antagonist.
A pharmaceutical preparation comprising:
- a covalent conjugate of a C8-C26 uunbranched, naturally occurring fatty acid and a noncentral nervous system active agent, and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.