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OwnerNils Reinton, Sigurd Orstavik +4inventors
InventorsNils Reinton, Sigurd Orstavik, Trine B Haugen, Tore Jahnsen, Kjelil Tasken, Bjorn S Skalhegg
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The cloning of a novel human Cα isoform, identified as the human Cα-s protein on the basis of its similarity to a recently characterized Cα isoform which was identified by purification and peptide sequencing of Cα from ovine sperm. The human Cα-s protein was present in testis and ejaculated sperm and Cα-s localized to the midpiece of human sperm. A cDNA sequence encodes a Cα-s protein and includes the specific nucleotide sequence shown in SEQ ID NO:1, wherein the protein is a new splice variant of Cα catalytic subunit of cAMP dependent protein kinase.
A cDNA sequence encoding a Cα-s protein comprising the nucleotide sequence SEQ ID NO 1, wherein said protein is a new splice variant of a Cα catalytic subunit of cAMP dependent protein kinases.
The specific amino acid sequence of SEQ ID NO:
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