Bot1: target for antifungal agents

Abstract

We have discovered a target protein which is conserved in fungi and essential for cell viability, cell growth, the control of cell morphogenesis, and combinations thereof. An antifungal agent targets the protein in a fungus, but not an infected host. This protein is encoded by the bot1 gene in Schizosaccharomyces pombe, Saccharomyces cerevisiae, and Candida albicans but is not detected in a filamentous fungus.

Dependencies are inferred from the claim text.