US 2004/0106125 A1Published application

Neurotransmission-associated proteins

OwnerBrendan M Duggan, Cynthia D Honchell +14inventors

InventorsBrendan M Duggan, Cynthia D Honchell, Craig H Ison, Kavitha Thangavelu, Dyung Aina M Lu, Mariah R Baughn, Preeti G Lal, Henry Yue, Y Tom Tang, Bridget A Warren, Ernestine A Lee, Jennifer A Griffin, Ian J Forsythe, Narinder K Chawla, Xin Jiang, Alan A Jackson

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Abstract

The invention provides human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

Claims71

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-8,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-5 and SEQ ID NO:7-8,
c) a polypeptide comprising a naturally occurring amino acid sequence at least 92% identical to the amino acid sequence of SEQ ID NO:6,
d) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-8, and
e) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-8.

2 more elements

Dependencies are inferred from the claim text.