Monovalent-selective cation exchangers as oral sorbent therapy

Abstract

The present invention relates to compounds and methods of treating patients exhibiting high levels serum toxins. The present invention finds particularly advantageous use for patients suffering from renal and/or liver dysfunction. The present invention includes administering to such patients a zirconium-silicate sorbent in amounts sufficient to reduce one or more of the levels of the serum toxins. The zirconium-silicate sorbent can function as a cation exchanger and exchange one or more cations and adsorb cationic toxics, such as, ammonium cations, potassium cations, sodium cations, calcium cations, magnesium cations, from the patient. Additionally, the zirconium-silicate sorbent can be combined with one or more of a carbon agent (or charcoal), zinc oxide and/or agent to enhance the intestine permeability such as a non absorbable alcohol.

Dependencies are inferred from the claim text.