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US 2004/0105874 A1Published application
Preparations for topical skin use and treatment
AssigneesDow Corning Corporation, Genencor International, Inc.
InventorsRichard R. Bott, Mark S. Gebert, Paal Christian Klykken, Isabelle Mazeaud, Xavier Jean-Paul Thomas
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Abstract
Topical preparations for release of an active agent and to methods of making and using the topical preparations are provided. The preparations may have an internal phase dispersed within an external phase. The internal phase may be a hydrophilic carrier and an active agent. The external phase may be a silicone matrix.
Claims67
A topical preparation comprising:
- an internal phase;
- and
- an external phase;
- wherein:
- said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier and at least one active agent;
- and
- said external phase comprises a silicone matrix.
5 more elements
A method of forming a topical preparation, comprising:
- preparing an internal phase, wherein said internal phase comprises at least one hydrophilic carrier and at least one active agent;
- preparing an external phase, wherein said external phase comprises a silicone matrix;
- dispersing said internal phase within said external phase to form said topical preparation.
A method of providing an active agent topically, comprising:
- providing a topical preparation, wherein said topical preparation comprises an internal phase and an external phase;
- wherein:
- said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier and at least one active agent;
- and
- said external phase comprises a silicone matrix;
- placing said topical preparation in contact with the skin of a patient such that said active agent is released from said silicone matrix topically onto said skin of said patient.
4 more elements
The method as claimed in 66 further comprising:
- providing a second topical preparation comprising an internal phase and external phase, wherein:
- said internal phase is dispersed within said external phase;
- said internal phase comprises at least one hydrophilic carrier at at least one second active agent selected such said second active agent inhibits said active agent selected to remove necrotic tissue;
- said external phase comprises a silicone matrix;
- and
- said silicone matrix comprises a silicone adhesive;
- placing said second topical preparation on said skin of said patient around a wound on said skin;
- and
- adhering said topical preparation over said wound by contacting said topical preparation to said second topical preparation, wherein said skin of said patient around said wound is protected from said active agent selected to remove necrotic tissues.
6 more elements
Dependencies are inferred from the claim text.