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US 2004/0072775 A1Published application
Enhancing the sensitivity of tumor cells to therapies
OwnerRobert Sobol, Ruth Gjersetinventors
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Abstract
A method for enhancing the effect of a cancer therapy by introducing wild-type therapy-sensitizing gene activity into tumor cells having mutant therapy-sensitizing gene activity and subjecting the tumor cells to a cancer therapy such as chemotherapy, radiotherapy, biological therapy including immunotherapy, cryotherapy and hyperthermia.
Claims22
Method of increasing the effect of a cancer therapy, comprising the steps of:
- delivering wild-type therapy-sensitizing gene activity to a tumor cell characterized by loss of said wild-type therapy-sensitizing gene activity, and
- subjecting said tumor cell to said cancer therapy.
Dependencies are inferred from the claim text.