Glucopyranose derivatives and medicaments for preventing and/or treating HIV infection diseases comprising the same as an active ingredient

A medicament for preventing and/or treating HIV infectious diseases comprising, as an active ingredient, a glucopyranose derivative of formula (J):

• 169
• (wherein X represents an oxygen atom or a methylene group;
• R represents a hydrogen atom, a hydroxyl group, or a C1-4 alkoxy group;
• G represents:
• (1) a group of formula:
• 170
• (wherein R1 represents a single bond or a C2-20 oxycarbonylalkylene group;
• R2 represents hydrogen atom or a group of formula:
• 171
• (in each formula, the ring A represents a C5-15 carbon ring;
• R8 represents a hydrogen atom, a C1-7 alkyl group, a C1-7 alkoxy group, or a halogen atom;
• and m represents 1, 2 or 3);
• R3 represents a C1-20 alkylene group;
• and
• R4 represents a hydrogen atom or a group of formula:
• 172
• (in each formula, the ring B represents a C5-15 carbon ring;
• R9 represents a hydrogen atom, a C1-7 alkyl group, a C1-7 alkoxy group, or a halogen atom;
• and n represents 1, 2 or 3)), or
• (2) a group of formula:
• 173
• (wherein Y represents a single bond or a C 4 alkylene group;
• and p and q each independently represents an integer of 6 to 12);
• R5 represents a C2-20 oxycarbonylalkylene group;
• R6 represents a hydrogen atom or a group of formula:
• 174
• (wherein the ring A, R8 and m have the same meanings as described above), or a combination of R5-R6 represents a group of formula:
• 175
• (wherein Z represents a single bond or a C1-4 alkylene group;
• and r and s each independently represents an integer of 6 to 12);
• and
• R7 represents a hydrogen atom, a methyl group, a hydroxymethyl group, or a sulfoxymethyl group;
• with the proviso that
• (1) when R1 represents a C2-20 oxycarbonylalkylene group, R2 is bound to the alkyl group in R1,
• (2) when R5 represents a C2-20 oxycarbonylalkylene group, R6 is bound to the alkyl group in R5),
• or a non-toxic salt thereof;