Somatostatin and somatostatin agonists for treating insulin insensitivity and Syndrome X
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques
InventorsMichael Anthony Cawthorne, Yong-Ling Liu, Matthew V. Sennitt
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Abstract
The present invention relates to a method of treating insulin resistance or Syndrome X. The method includes the step of administering a therapeutically effective amount of a somatostatin or a somatostatin agonist to said patient. The invention also includes pharmaceutical compositions comprising a somatostatin or somatostatin agonist and the use of such products in the preparation of such compositions.
Claims35
A method of treating insulin resistance in a patient, said method comprising administering a therapeutically effective amount of somatostatin or a somatostatin agonist to said patient.
A method of decreasing insulin resistance in a patient, said method comprising administering a therapeutically effective amount of H-Cys-Phe-Phe-D-Trp-Lys-Thr-Phe-Cys-NH2, wherein a disulfide bond exists between the free thiols of two Cys residues.
A method of treating Syndrome X in a patient, said method comprising administering a therapeutically effective amount of somatostatin or a somatostatin agonist to said patient.
A method of decreasing Syndrome X in a patient, said method comprising administering a therapeutically effective amount of H-Cys-Phe-Phe-D-Trp-Lys-Thr-Phe-Cys-NH2, wherein a disulfide bond exists between the free thiols of two Cys residues.
A pharmaceutical composition comprising a therapeutically effective amount of somatostatin;
- or a somatostatin agonist;
- or H-Cys-Phe-D-Trp-Lys-Thr-Phe-Cys-NH2, wherein a disulfide bond exists between the free thiols of the two Cys residues.
Use of a somatostatin, or a somatostatin agonist or H-Cys-Phe-Phe-D-Trp-Lys-Thr-Phe-Cys-NH2, wherein a disulfide bond exists between the free thiols of the two Cys residues, in the formulation of a pharmaceutical composition for use in the treatment of insulin resistance and/or Syndrome X.
A pharmaceutical composition substantially as hereinbefore described with reference to the Examples.
Dependencies are inferred from the claim text.