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US 2004/0072241 A1Published application
Methods for detecting B. anthracis infection
AssigneeBiosite Diagnostics, a Delaware corporation
InventorsGunars Edwin Valkirs, Kenneth Buechler
Life of this patent
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Abstract
This invention pertains to methods for detecting B. anthracis and antibodies to B. anthracis, the causative agent of anthrax, in a subject
Claims56
A method for the detection of an anti-B. anthracis antibody present in a biological sample, the method comprising:
- (i) contacting a biological sample from an animal with an affinity agent comprising an epitope recognized by a first antibody that specifically binds to SEQ ID NO:
- 1, wherein the affinity agent forms a first complex with the anti-B. anthracis antibody if the anti-B. anthracis antibody is present in the sample;
- and
- (ii) detecting the presence or absence of the first complex, wherein the presence of the first complex indicates the presence of antibodies to B. anthracis in the sample.
1 more element
A kit for the detection of an anti-B. anthracis antibody in a biological sample, the kit comprising an affinity agent immobilized on a solid support, the affinity agent comprising an epitope recognized by a first antibody that specifically binds to SEQ ID NO:
- 1, wherein the affinity agent forms a first complex with the anti-B. anthracis antibody if the anti-B. anthracis antibody is contacted to the affinity agent.
Dependencies are inferred from the claim text.