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US 2004/0072189 A1Published application
Prognostic indicator
OwnerArthur John Smith, Philip Spencer Rudlandinventors
Life of this patent
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Abstract
A prognostic indicator for metastasis comprises an antibody directed against ostepontin.
Claims27
A method for detecting the absence of metastatic cancer comprising the steps of:
- i) contacting a subject sample comprising epithelial cells and/or lysates of epithelial cells from a primary tumour with a prognostic indicator comprising an antibody or a fragment thereof directed against osteopontin;
- and
- ii) detecting the formation of any complex between the subject sample and prognostic indicator.
A method as claimed in any previous claim wherein the method of diagnosis is for metastatic breast cancer.
A vaccine against metastatic cancer comprising an antigenic peptide derived from osteopontin.
A method of diagnosis for metastatic cancer comprising the steps of:
- i) contacting a subject sample comprising epithelial cells and/or lysates of epithelial cells from a primary tumour with a prognostic indicator comprising an antibody or a fragment thereof directed against osteopontin;
- and
- ii) detecting the formation of any complex between the subject sample and prognostic indicator.
Dependencies are inferred from the claim text.