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US 2004/0071861 A1Published application
Method of manufacturing a stent coating and a method of using the stent
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsEvgenia Mandrusov, Paul Consigny, Syed Faiyaz Ahmed Hossainy, Dary Mirzaee
Life of this patent
Estimating the term…
Abstract
Stents and a method of using the stents to increase blood flow to ischemic tissues in a patient are disclosed.
Claims22
A stent, comprising:
- a tubular body having an outer surface for contacting the wall of a vessel and an inner surface;
- a first coating supported by said inner surface and containing an angiogenic substance for the release of said angiogenic substance in said vessel;
- and
- a second coating supported by said outer surface and containing a therapeutic substance for applying said therapeutic substance to said wall of said vessel.
1 more element
A stent for implanting in a blood vessel comprising a tubular structure having an inner surface and an outer surface, comprising:
- a first therapeutic substance carried by the inner surface for being released downstream with the flow of blood;
- and
- a second therapeutic substance, different from the first therapeutic substance, carried by the outer surface for application to the blood vessel wall,
- wherein the first therapeutic substance facilitates therapeutic angiogenesis and wherein the second therapeutic substance inhibits migration or proliferation of smooth muscle cells.
1 more element
A method for increasing blood flow to ischemic tissues located downstream from an occluded region in a blood vessel, comprising:
- implanting a stent in the blood vessel at a location upstream from the ischemic tissues, the stent having an inner surface carrying an angiogenic substance.
Dependencies are inferred from the claim text.