Fenofibrate-containing composition
AssigneeAska Pharmaceutical Co., Ltd.
InventorMasaru Okamoto
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Abstract
A novel fenofibrate-containing composition having equivalent bioavailability, when compared to conventional capsules, is effective in reducing the size of the conventional capsule preparations. The fenofibrate-containing composition comprises the following formula: 1 (a) fenofibrate 100 parts by weight, (b) a solid surfactant 3 to 4 parts by weight, (c) lactose 1 to 2 parts by weight, and (d) magnesium stearate 1 to 2 parts by weight, in admixture with a binder and a disintegrator, wherein the sum of said binder and said disintegrator is 17 to 20 parts by weight, and the fenofibrate and the solid surfactant are co-micronizates.
Claims4
A fenofibrate-containing composition comprising the following formulation:
- 7 (a) fenofibrate 100 parts by weight, (b) a solid surfactant 3 to 4 parts by weight, (c) lactose 1 to 2 parts by weight and (d) magnesium stearate 1 to 2 parts by weight
- in admixture with a binder and a disintegrator, wherein the sum of said binder and said disintegrator is 17 to 20 parts by weight, and the fenofibrate and the solid surfactant are co-micronizates.
Dependencies are inferred from the claim text.